PGT: what genetic tests of embryos are for
Preimplantation genetic tests seek specific information before transferring an embryo. PGT-A, PGT-M, and PGT-SR answer different questions. None rule out all diseases or guarantee a healthy baby.
PGT: what genetic tests of embryos are for
- The tests are not interchangeable
- Their limits
- What to clarify before authorizing
- Related articles
- Sources
PGT is the general name for genetic tests that can be performed on embryos before transfer. The first question is what you want to investigate and why.
The tests are not interchangeable
- PGT-A: evaluates the number of chromosomes in the analyzed sample.
- PGT-M: looks for a known specific genetic condition.
- PGT-SR: studies alterations related to structural rearrangements of chromosomes.
Their limits
A test may have inconclusive results or require additional counseling. The sample does not allow ruling out all health problems. PGT-A should not be presented as an improvement of the result for everyone.
What to clarify before authorizing
Ask about the indication, the risks of obtaining the sample, the cost, and the possible decisions based on each result. Confirm how complex results would be handled and what tests could be proposed during pregnancy.
The decision needs medical counseling and, when appropriate, genetic counseling. You can ask for time and explanations to understand the options before authorizing a test.
Related articles
- What is a blastocyst
- Prenatal tests: detection is not diagnosis
- Before accepting additional tests or treatments
